Process for preparing 4-amino-2- (2,6-dioxopiperidin-3-yl) isoindoline-1,3-dione compound

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专利权人:

セルジーン コーポレイション

发明人:

ゲオルゲ ダブリュ． ムルレル,マノハル ティー． サインダネ,チュアンスヘング ゲ,ロゲル チェン,ゲオルゲ ダブリュ. ムルレル,マノハル ティー. サインダネ

申请号：

JP2012193866

公开号：

JP5543555B2

申请日:

2012.09.04

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

The present invention provides new processes for the preparation of unsubstituted and substituted 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione compounds which are useful, for example, for preventing or treating diseases or conditions related to an abnormally high level or activity of TNF-±. The invention can provide improved and/or efficient processes for the commercial production of unsubstituted and substituted 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione compounds, including, but not limited to, unsubstituted 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione.

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