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INFECTION ACTIVATED WOUND CARING COMPOSITIONS AND DEVICES
专利权人:
Gerald F. Swiss
发明人:
Gerald F. Swiss,Stefan Schwabe,Robert M. Moriarty
申请号:
US13607431
公开号:
US20130064772A1
申请日:
2012.09.07
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Provided are wound caring compositions and devices containing a pH-sensitive, preferably acid degradable, components contained in a water-permeable and hydronium ion permeable material. The pH-sensitive component encloses an antibiotic which is released to the wound upon infection by a microorganism at the wound site, and/or encloses a pH indicator. The antibiotic release is triggered by the microorganisms production of CO2 at the wound site which forms carbonic acid, lowers the pH at the pH sensitive components, and thus results in rupture of the liposome.
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