PROTEINES DE FUSION DE FRAGMENTS DE PROTEINES HUMAINES UTILISEES AFIN DE CREER DES COMPOSITIONS DE FC D'IMMUNOGLOBULINE MULTIMERISEE DE MANIERE ORDONNEE AVEC UNE LIAISON DE RECEPTEUR FC AMELIOREE
The present invention involves a series of fully recombinant multimerized forms of immunoglobulin Fc which thereby present polyvalent immunoglobulin Fc to immune cell receptors. The fusion proteins exist as both homodimeric and highly ordered multimeric fractions, termed stradomers. The invention involves fusion proteins that bind to Fc?Rs and complement and that are useful in the treatment and prevention of disease.