Tobias POEHLMANN,Rolf GUENTHER,Michael REUTER,Mirko LUDWIG
申请号：
US15503810
公开号：
US20200230251A1
申请日:
2015.08.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
What is described is a peptide for use in the reduction of side-effects in form of immunostimulatory reactions/effects which occur with gene therapy, wherein the peptide is coupled to a nucleic acid molecule used in gene therapy. Furthermore, such a peptide is described for use in the reduction of side-effects in form of immunostimulatory reactions/effects which occur with gene therapy, wherein the peptide is coupled to a nucleic acid molecule used in gene therapy, wherein the immunostimulatory reactions/effects are induced by activation of IFIT1/2, IRF9, TLR3, TLR7, TLR8 or PKR.
