Tobias Pöhlmann,Rolf Günther,Michael Reuter,Mirko Ludwig
申请号：
DE112015003749
公开号：
DE112015003749A5
申请日:
2015.08.13
申请国别(地区):
DE
年份:
2018
代理人:
摘要：
What is described is a peptide for use in the reduction of side-effects in form of immunostimulatory reactions/effects which occur with gene therapy, wherein the peptide is coupled to a nucleic acid molecule used in gene therapy. Furthermore, such a peptide is described for use in the reduction of side-effects in form of immunostimulatory reactions/effects which occur with gene therapy, wherein the peptide is coupled to a nucleic acid molecule used in gene therapy, wherein the immunostimulatory reactions/effects are induced by activation of IFIT1/2, IRF9, TLR3, TLR7, TLR8 or PKR.
