Ramachandra G. Naik,Elizabeth S. Ommen,James Michael Rusnak,Steven G. Terra
申请号：
US16892986
公开号：
US20200297692A1
申请日:
2020.06.04
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to certain SGLT-2 inhibitors, such as ertugliflozin or a co-crystal or a pharmaceutically acceptable salt thereof, for treating and/or preventing metabolic disorders, such as type 1 or type 2 diabetes mellitus or pre-diabetes, in patients with renal impairment or chronic kidney disease (CKD). The present invention also relates to methods for preventing neuronal damage following the incidence of ischemic stroke and close-head traumatic brain injury in animals comprising the step of administering to an animal, in need of such treatment, a therapeutically effective amount of ertugliflozin or a co-crystal or a pharmaceutically acceptable salt thereof.
