Fusion constructs and use of same to produce antibodies with increased Fc receptor binding affinity and effector function

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专利权人:

GlycArt Biotechnology AG

发明人:

Umana, Pablo,Bruenker, Peter,Ferrara, Claudia,Suter, Tobias

申请号：

AU2010200408

公开号：

AU2010200408C1

申请日:

2010.02.04

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

#$%^&*AU2010200408C120121101.pdf#####ABSTRACT The present invention relates to the field of glycosylation engineering of proteins. More particularly, the present invention relates to nucleic acid molecules, including fusion constructs, having catalytic activity and the use of same in glycosylation engineering of host cells to generate polypeptides with improved therapeutic properties, including antibodies with increased Fc receptor binding and increased effector function. 04/02/10

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中国工程科技知识中心

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