Pablo Umaña,Peter Bruenker,Claudia Ferrara,Tobias Suter
申请号：
US13759925
公开号：
US08859234B2
申请日:
2013.02.05
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to the field of glycosylation engineering of proteins. More particularly, the present invention relates to nucleic acid molecules, including fusion constructs, having catalytic activity and the use of same in glycosylation engineering of host cells to generate polypeptides with improved therapeutic properties, including antibodies with increased Fc receptor binding and increased effector function.
