ANTICORPS ANTI-HER3 HUMAINE ET LEURS UTILISATIONS

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专利权人:

UNIVERSITE DE MONTPELLIER;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);GAMAMABS PHARMA;INSTITUT REGIONAL DU CANCER DE MONTPELLIER

发明人:

CHARDES, THIERRY,DUBREUIL, OLIVIER,PELEGRIN, ANDRE,LARBOURET, CHRISTEL,PROST, JEAN-FRANCOIS,BARRET, JEAN-MARC,DEGOVE, STEPHANE

申请号：

CA2985143

公开号：

CA2985143A1

申请日:

2016.05.02

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The present disclosure relates to a neuregulin non competitive allosteric anti-human-HER3 antibody having a human constant region； and less than 65 % of the glycan structures carried by the glycosylation site of the antibody comprises a fucose molecule. The antibody is characterized by its variable sequences.

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