ANTI-HUMAN-HER3 ANTIBODIES AND USES THEREOF

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专利权人:

INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM);UNIVERSITE DE MONTPELLIER;GAMAMABS PHARMA;INSTITUT REGIONAL DU CANCER DE MONTPELLIER

发明人:

Thierry CHARDÈS,Olivier DUBREUIL,André PELEGRIN,Christel LARBOURET,Jean-François PROST,Jean-Marc BARRET,Stéphane DEGOVE

申请号：

US15571720

公开号：

US20180155433A1

申请日:

2016.05.02

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present disclosure relates to a neuregulin non competitive allosteric anti-human-HER3 antibody having a human constant region； and less than 65% of the glycan structures carried by the glycosylation site of the antibody comprises a fucose molecule. The antibody is characterized by its variable sequences.

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