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Immunotoxins, formulations thereof and their use in medicine
专利权人:
Xenikos BV
发明人:
VAN HOOREN, Henricus Gerardus,FRIJLINK, Maarten Jaap,VAN OOSTERHOUT, Ypke Vincentius Johannes Maria
申请号:
AU2018357984
公开号:
AU2018357984A2
申请日:
2018.10.31
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The present invention provides a composition comprising a first antibody molecule that specifically recognises CD3 and a second antibody molecule that specifically recognises CD7, for use in a method of treatment, or preventative treatment,of viral infection or viral reactivation in a mammalian subject undergoing immunomodulatory treatment, wherein the first and second antibody molecules are each provided with a toxic moiety. Also provided is a method of treating a mammalian subject having, or being at risk of developing, chronic Graft versus Host disease (cGVHD). Also provided is a related pharmaceutical composition.
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