VAN HOOREN, HENRICUS GERARDUS,FRIJLINK, MAARTEN JAAP,VAN OOSTERHOUT, YPKE VINCENTIUS JOHANNES MARIA
申请号：
CA3080873
公开号：
CA3080873A1
申请日:
2018.10.31
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention provides a composition comprising a first antibody molecule that specifically recognises CD3 and a second antibody molecule that specifically recognises CD7, for use in a method of treatment, or preventative treatment,of viral infection or viral reactivation in a mammalian subject undergoing immunomodulatory treatment, wherein the first and second antibody molecules are each provided with a toxic moiety. Also provided is a method of treating a mammalian subject having, or being at risk of developing, chronic Graft versus Host disease (cGVHD). Also provided is a related pharmaceutical composition.
