An image pickup apparatus includes a silicon layer, a wire layer that contains an insulator having a lower dielectric constant than silicon oxide, a cover glass that covers a light receiving portion on a light receiving surface of the silicon layer, and a silicon substrate that covers a back surface of the wire layer, in which a guard ring is formed along an outer edge on the wire layer, a through-hole having a bottom surface that is configured by an electrode pad configured by a conductor of the wire layer and having an outer periphery portion in contact with the silicon layer over a whole periphery is provided in a region of the silicon layer that is not covered with the cover glass, and the insulator of the wire layer is not exposed to an inner surface of the through-hole.