ALLEY, STEPHEN CHARLES,TORGOV, MICHAEL,SUN, MICHAEL
申请号:
CA2558399
公开号:
CA2558399C
申请日:
2005.03.02
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
A protein containing one or more activatable groups, e.g., an antibody, issubjected to partial or complete reduction of one or more such bonds to formreactive groups; the resulting protein is reacted with a drug which isreactive with some of the reactive groups, such as certain radiometals,chelating agents, and toxins, so as to form a conjugate useful in, e.g., invitro diagnosis, in vivo imaging, and therapy.