BRANDL, Trixi,RAMAN, Prakash,RIGOLLIER, Pascal,SEEPERSAUD, Mohindra,SIMIC, Oliver
申请号：
ES10722776
公开号：
ES2603744T3
申请日:
2010.04.09
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A compound according to Formula (II): ** Formula ** and stereoisomers thereof； wherein R3 is C1-C6 alkyl or C2-C6 alkenyl R1 and R2 are independently hydrogen or are independently selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy and C3-C7 cycloalkyl alkyl C0-C2 alkyl, each one of which is substituted with 0, 1 or 2 moieties selected from halogen and C1-C4 alkyl； or R1 and R2, taken together with the nitrogen atom to which they are attached, form a saturated, unsaturated or aromatic heterocyclic ring having 0, 1 or 2 additional heteroatoms in the ring independently selected from N, O or S and said heterocyclic ring it has from 4 to 7 total atoms in the ring, said heterocycle having 0, 1, 2 or 3 substituents independently selected from C1-C4 alkyl, C1-C4 haloalkyl, C2-C4 alkenyl, C2-C4 alkynyl, hydroxyl, C1- alkoxy C4, C1-C4 haloalkoxy, amino, mono- and C1-4alkyl alkyl, C1-C4 aminoalkyl, C1-C4 alkanoyl C1-C4 aminoalkyl； R4 is C1-C8 alkyl, C3-C8 cycloalkyl or a saturated 5 or 6 heterocyclic ring having 1 or 2 ring heteroatoms independently selected from N, O or S, each of which is substituted with 0-2 groups C1-C4 alkyl； J is a divalent moiety of the formula: ** Formula ** R5 is C1-C8 alkyl, C3-C8 cycloalkyl, or a saturated 5- or 6-membered heterocyclic ring having 1 or 2 ring heteroatoms independently selected from N, O or S, each of which is substituted with 0-2 C1-C4 alkyl groups； R6 is hydrogen or C1-C4 alkyl； G is a group of the formula -E-R7； E is a bond, CH2, C (O), S (O) 2, C (R9) 2C (O) or C (O) C (R9) 2, R7 is selected from the group consisting of C1-C6 alkyl , C1-C6 haloalkyl, C3-C7 cycloalkyl C0-C2 alkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, C3-C7 cycloalkyl C0-C2 alkoxy, mono- and dialkyl-C1-C6 amino, -S (O) 2R10, -N (R9) S (O) 2R10 monocyclic or bicyclic heterocycle, and monocyclic or bicyclic aryl, in which each moiety is unsubstituted or substituted with 1, 2 or 3 R8 groups, each of the R8 moieties is independently selected from the group that
