CHARMOT, DOMINIQUE,多米尼克.沙爾莫,JACOBS, JEFFREY, W. W,杰弗里.,LEADBETTER, MICHAEL, ROBERT,.雅各布斯,NAVRE, MARC,邁克爾.羅伯特.利德貝特,CARRERAS, CHRIS,馬克.納夫雷亞,BELL, NOAH,克里斯.卡雷拉斯,諾厄.貝爾
申请号：
HK14111257.9
公开号：
HK1198162A
申请日:
2012.07.20
申请国别(地区):
HK
年份:
2015
代理人:
摘要：
The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (PPAR) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension. The present disclosure is also directed to compounds and methods for the treatment of gastrointestinal tract disorders, including the treatment or reduction of pain associated with gastrointestinal tract disorders.
