Graham Beaton,Fabio C. Tucci,Satheesh B. Ravula,Chandravadan R. Shah,Hiep Luu
申请号：
US16010755
公开号：
US10526298B2
申请日:
2018.06.18
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Heterocyclic compounds are described that are lysophosphatidic acid receptor ligands that are useful in the treatment of lysophosphatidic acid receptor-dependent diseases and conditions, including but not limited to diseases involving fibrosis, such as fibrosis of the heart, kidney, liver and lung, and scleroderma； inflammatory diseases such as diabetic nephropathy and nonalcoholic steatohepatitis (NASH)； ocular diseases such as diseases involving retinal degeneration； nerve diseases such as pruritus and pain.
