Inc.;H. Lee Moffitt Cancer Center And Research Institute
发明人:
ANTONIA, Scott,CHIAPPORI, Alberto
申请号：
EP16774419
公开号：
EP3277325A4
申请日:
2016.04.04
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
A method is disclosed for treating small cell lung cancer (SCLC) in a subject that involves administering to the subject a therapeutically effective amount of dendritic cells engineered to overexpress p53. In some embodiments, the method further involves administering to the subject a therapeutically effective amount of all-trans-retinoic acid (ATRA). The method can also involve administering to the subject a therapeutically effective amount of an immune checkpoint inhibitor.
