David M. Shanahan,John J. Nemunaitis, I,Neil Senzer,Phillip B. Maples,Donald Rao
申请号：
US14535789
公开号：
US09528991B2
申请日:
2014.11.07
申请国别(地区):
US
年份:
2016
代理人:
摘要：
In certain embodiments, the invention provides methods for treating cancer, comprising: obtaining a specimen of cancer tissue and normal tissue from a patient extracting total protein obtaining a protein expression profile identifying over-expressed proteins comparing the protein expression profile to a gene expression profile identifying at least one prioritized protein target designing a first RNA interference expression cassette designing a first RNA interference expression cassette to modulate the expression of at least one gene encoding incorporating the first cassette into a delivery vehicle and providing a patient with an effective amount of the first delivery vehicle.
