Disclosed is a composition including at least one siRNA, the siRNA hybridising with a coding or non-coding mNRA, in which it induces degradation or inhibits translation, the expression of the mRNA or of the protein for which it codes being implicated in a pathology, for the use of same in the prevention and/or the treatment of the pathology, the composition being formulated for a continuous systemic administration mode, and a device including such an administration mode.
