DEODHAR, MANDAR,FINDLAY, ALISON DOROTHY,FOOT, JONATHAN STUART,JAROLIMEK, WOLFGANG,MCDONALD, IAN ALEXANDER,ROBERTSON, ALAN DUNCAN,TURNER, CRAIG IVAN
申请号:
CA2871793
公开号:
CA2871793A1
申请日:
2013.04.05
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention is related to the preparation and pharmaceutical use of substituted 3-haloallylamine derivatives as SSAO/VAP-1 inhibitors having the structure of Formula (I), as defined in the specification. The invention also relates to methods of using compounds of Formula (I), or pharmaceutically acceptable salt or derivatives thereof, for the treatment of a variety of indications, e.g., inflammatory diseases, ocular diseases, fibrotic diseases, diabetes-induced diseases and cancer.