Mandar Deodhar,Alison Dorothy Findlay,Jonathan Stuart Foot,Wolfgang Jarolimek,Ian Alexander Mcdonald,Alan Duncan Robertson,Craig Ivan Turner
申请号:
US15054243
公开号:
US09815782B2
申请日:
2016.02.26
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention is related to the preparation and pharmaceutical use of substituted 3-haloallylamine derivatives as SSAO/VAP-1 inhibitors having the structure of Formula I, as defined in the specification:The invention also relates to methods of using compounds of Formula I, or pharmaceutically acceptable salt or derivatives thereof, for the treatment of a variety of indications, e.g., inflammatory diseases, ocular diseases, fibrotic diseases, diabetes-induced diseases and cancer.