The present invention relates to an oral complex preparation comprising: a capsule containing a fat-soluble first drug and a solid preparation containing a second drug, the solid preparation being embedded into the capsule and including an oil-proof material coating layer on the surface thereof.The oral complex preparation of the present invention prepared by embedding the solid preparation including the oil-proof material coating layer on the surface thereof and containing the second drug into the capsule containing the fat-soluble first drug enables two types of drug ingredients to be simultaneously administered. At this time, the oral complex preparation of the present invention can independently transfer each of two types of the active ingredients to a desired region without loss of the active ingredients since the oral complex preparation by enabling the oil-proof material coating layer on the surface of the solid preparation to block elution of the active ingredients of the solid preparation by the fat-soluble first drug or occurrence of side effects with the fat-soluble first drug.
