PRATHER, Randall S.,WELLS, Kevin D.,WHITWORTH, Kristin M.,PRATHER RANDALL S,WELLS KEVIN D,WHITWORTH KRISTIN M
申请号：
DK12785983
公开号：
DK2709445T3
申请日:
2012.05.16
申请国别(地区):
DK
年份:
2018
代理人:
摘要：
The disclosure relates to a genetically modified swine wherein at least one allele of a SIGLEC1 gene has been inactivated and/or at least one allele of a CD163 gene has been inactivated. Genetically modified swine having both alleles of the SIGLEC1 gene and/or both alleles of a CD163 gene inactivated are resistant to porcine reproductive and respiratory syndrome virus (PRRSV). Methods for producing such transgenic swine are also provided.
