CHRISTOPHER MEHLIN,JAMES F. SMOTHERS,KENNETH ALLAN BRASEL,STEPHEN FOSTER,DOUGLAS PAT CERRETTI,JILIN SUN
申请号:
PT08798203
公开号:
PT2188313T
申请日:
2008.08.19
申请国别(地区):
PT
年份:
2017
代理人:
摘要:
Antigen binding proteins that bind to human c-fms protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of c-fms to CSF-I, reduce monocyte migration into tumors, and reduce the accumulation of tumor-associated macrophages.