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STABLE INJECTABLE COMPOSITIONS
专利权人:
Lawrence John PENKLER
发明人:
Lawrence John PENKLER,Barry Paul Daisley
申请号:
US13153283
公开号:
US20120142779A1
申请日:
2011.06.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
This invention relates to a stable parenteral aqueous solutions comprising either (a) diclofenac or a pharmaceutically acceptable diclofenac salt and a cyclodextrin, or (b) an inclusion complex of diclofenac or a pharmaceutically acceptable diclofenac salt and a cyclodextrin, or a mixture of (a) and (b), which are suitable for intramuscular and intravenous administration. The solutions contain diclofenac or diclofenac salt, cyclodextrin, and an antioxidant selected from monothioglycerol, or a combination of ethylene diamine tetra-acetic acid and N-acetyl-cysteine.
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