TOMOMICHI FUTO,KAZUHIRO SAITO,TETSUO HOSHINO,MASUHISA HORI
申请号：
IN201638022889
公开号：
IN201638022889A
申请日:
2016.07.04
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
A sustained-release composition in which a physiologically active substance is substantially uniformly dispersed in a microcapsule comprised of a lactic acid polymer or a salt thereof, wherein the physiologically active substance is contained in an amount of 15 to 35 (weight/weight) % to the total microcapsules, weight-average molecular weight (Mw) of the lactic acid polymer is about 19,000 to about 27,000, the physiologically active substance is a peptide of formula: 5-oxo-Pro-His-Trp-Ser-Tyr-DLeu-Leu-Arg-Pro-NH-C2H5 or a salt thereof, and the sustained-release composition further contains stearic acid.
