TOMOMICHI FUTO,KAZUHIRO SAITO,TETSUO HOSHINO,MASUHISA HORI
申请号：
MYPI 20092544
公开号：
MY148370A
申请日:
2007.12.17
申请国别(地区):
MY
年份:
2013
代理人:
摘要：
SUSTAINED-RELEASE COMPOSITIONS WHEREIN A WATER-SOLUBLE PHYSIOLOGICALLY ACTIVE PEPTIDE IS SUBSTANTIALLY UNIFORMLY DISPERSED IN A MICROCAPSULE COMPRISED OF A LACTIC ACID POLYMER OR A SALT THEREOF, AND THE PHYSIOLOGICALLY ACTIVE SUBSTANCE IS CONTAINED IN AN AMOUNT OF 15 TO 35 WT/WT% TO THE TOTAL MICROCAPSULES AND WEIGHT-AVERAGE MOLECULAR WEIGHT (MW) OF THE LACTIC ACID POLYMER IS ABOUT 11,000 TO ABOUT 27,000, WHICH IS CHARACTERIZED BY HAVING A HIGH CONTENT OF THE PHYSIOLOGICALLY ACTIVE SUBSTANCE, AND SUPPRESSION OF THE INITIAL EXCESSIVE RELEASE WITHIN ONE DAY AFTER THE ADMINISTRATION AND A STABLE DRUG SUSTAINED-RELEASE OVER A LONG PERIOD OF TIME, AND METHOD FOR PRODUCING THE SAME.
