John Edgar Dick,Liqing JIN,Gino Luigi VAIRO,David Paul GEARING,Samantha Jane BUSFIELD
申请号：
US15233260
公开号：
US20170029515A1
申请日:
2016.08.10
申请国别(地区):
US
年份:
2017
代理人:
摘要：
A method for inhibition of leukemic stem cells expressing IL-3Rα (CD123), comprises contacting the cells with an antigen binding molecule comprising a Fc region or a modified Fc region having enhanced Fc effector function, wherein the antigen binding molecule binds selectively to IL-3Rα (CD123). The invention includes the treatment of a hematologic cancer condition in a patient by administration to the patient of an effective amount of the antigen binding molecule.
