TAKEDA VACCINES INC.;THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
Livengood Jill A.,Kinney Claire Y.,Stinchcomb Dan T.,Kinney Richard M.
申请号:
NZ63086914
公开号:
NZ630869A
申请日:
2014.03.12
申请国别(地区):
NZ
年份:
2017
代理人:
摘要:
Disclosed is nucleic acid sequences encoding modified live, attenuated dengue-2 viruses defined by the sequences disclosed in the specification. Also disclosed is polypeptides encoded by said nucleotides, pharmaceutical compositions comprising the viruses and the use of said viruses in the manufacture of immunogenic compositions for inducing an immune response to a dengue virus in a subject.