1. Compounds made from Pizarozol Amines derivatives with LRRK2 quinase inhibitor activity, pharmaceutical ingredients containing these substances and used in the treatment of Parkinson's disease, Alzheimer's disease and lateral Amy's sclerosis (ELA).
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
DING, Xiao,LIU, Qian,SANG, Yingxia,STASI, Luigi Piero,WAN, Zehong,ZHAO, Baowei,EDGE, Colin Michael
申请号:
CL2016001895
公开号:
CL2016001895A1
申请日:
2016.07.26
申请国别(地区):
CL
年份:
2016
代理人:
摘要:
Pyridine-2-amines (2,3-D) pyridine-2-amines as LRRK2 waistband active inhibitors; drug synthesis; and compounds used in the treatment of Parkinson's disease.COMPUESTOS DERIVADOS DE PIRAZOLO PIRROLO[2,3-D]PIRIMIDIN-2-AMINA, COMO INHIBIDORES DE LA ACTIVIDAD DE LAS CINASAS LRRK2; COMPOSICIÓN FARMACÉUTICA; Y SU USO PARA EL TRATAMIENTO DE LA ENFERMEDAD DE PARKINSON.