FERNANDEZ MOLINA, LUIS ENRIQUE,VAZQUEZ LOPEZ, ANA MARIA,PEREZ RODRIGUEZ, ROLANDO,PEREZ GONZALEZ, ALEXIS,CARR PEREZ, ADRIANA,DIAZ RODRIGUEZ, YILDIAN,ALFONSO FERNANDEZ, MAURO A.,ADRIANA MARIA ROJAS DEL
申请号：
MYPI 20021239
公开号：
MY157372A
申请日:
2002.04.05
申请国别(地区):
MY
年份:
2016
代理人:
摘要：
THE PRESENT INVENTION IS RELATED TO HUMAN MEDICINE AND MORE SPECIFICALLY TO CANCER IMMUNOTHERAPY. THIS INVENTION ALSO RELATES TO PROTECTIVE AND THERAPEUTIC VACCINES THAT INDUCE AN IMMUNE RESPONSE TO TUMORS THAT EXPRESS GANGLIOSIDES AND METHODS TO REDUCE TUMOR BURDEN. @THE METHODS DESCRIBED IN THE PRESENT INVENTION ARE BASED ON THE SYNERGIC THERAPEUTIC EFFECT OBTAINED BY COMBINATION OF IDIOTYPIC VACCINES. IDIOTYPIC VACCINES OF THE PRESENT INVENTION COMPRISES MURINE ANTI-GANGLIOSIDE ANTIBODIES (Ab1), SPECIFIC MURINE ANTI-IDIOTYPE ANTIBODIES AGAINST THE ANTI-GANGLIOSIDE (Ab2) AND GANGLIOSIDE VACCINES. @THE PRESENT INVENTION ALSO RELATES TO METHODS EFFECTIVE IN SUBJECTS TO REDUCE THE BURDEN OF TUMORS THAT EXPRESS GANGLIOSIDES.
