Harriet Robinson,Arban Domi,Michael Hellerstein,Farshad Guirakhoo,Nathanael Paul McCurley
申请号：
US16068527
公开号：
US20190290745A1
申请日:
2017.01.09
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The compositions and methods are described for generating an immune response to a tumor associated antigen such as MUC1. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a neoplasm expressing the tumor associated antigen in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat neoplasms and associated diseases.
