In accordance with one aspect of the disclosure, a surgical device includes: a handle portion including a movable handle an elongated tubular portion extending distally from the handle portion a first jaw having a first engagement surface a second jaw having a second engagement surface, wherein at least the first jaw moves between open and closed configurations, wherein the jaws are arranged to receive tissue therebetween when open and to exert force on tissue when in the closed configuration and a drive assembly operates to drive at least the first jaw to transition the jaws between the open and closed configurations, wherein the drive assembly actuates by the movable handle that has an initial position and at least first and second preset positions, wherein in the first preset position the jaws exert a first clamping force and in the second preset position the jaws exert a second clamping force that is greater than the first clamping force. In accordance with another aspect of the disclosure, a surgical device for treatment of parenchyma includes: a handle portion including a movable handle an elongated tubular portion extending distally from the handle portion, the elongated tubular portion having a transverse cross-sectional dimension at least at a distal region not exceeding 12 millimeters a first jaw at a distal portion of the device having a first engagement surface a second jaw at the distal portion of the device having a second engagement surface, wherein at least the first jaw is movable to transition the jaws between an open and closed configurations, wherein the jaws are arranged to receive parenchyma therebetween when open and to exert force on the tissue via the first and second engagement surfaces when in the closed configuration without causing blunt dissection of the parenchyma, wherein the first and second jaws in the closed configuration have a transverse cross-sectional dimension not exceeding 12 millimeters.Selon un aspect de linvention, un disp
