DOSENBACH, CORNELIA,GRASSBERGER, MAXIMILIAN DR,HARTMANN, OTTO,HORVATH, AMARYLLA,MUTZ, JEAN-PAUL,PENN, GERHARD,PFEFFER, SABINE,WIECKHUSEN, DIERK
申请号：
HU0003053
公开号：
HU227755B1
申请日:
1998.06.26
申请国别(地区):
HU
年份:
2012
代理人:
摘要：
33-Epichloro-33-desoxyascomycin of formula Iand various tautomeric or forms thereof, in crystalline form, such as Form A and Form B.Their preparation involves appropriately converting amorphous compound of formula I, or compound of formula I in other than Form A, or compound of formula I in other than Form B, respectively, from a solution thereof under crystallization-inducing conditions or conditions inducing preferential crystallization of Form A or B, respectively.Such crystals are particularly indicated for use in the preparation of topical galenical forms of the compound for pharmaceutical use, e.g. creams, emulsions and ointments.
