Trihydrochloride forms of a dihydropteridinone derivative and processes for preparation

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专利权人:

Boehringer Ingelheim International GmbH

发明人:

Schmid, Rolf,Sieger, Peter,Linz, Guenter,Grauert, Matthias

申请号：

AU2007213752

公开号：

AU2007213752B2

申请日:

2007.02.07

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The present invention relates to a specific salt of a dihydropteridione derivative, namely the trihydrochloride salt of the compound N-[trans-4-[4-(cyclopropylmethyl)-1- piperazinyl]cyclohexyl]-4-[[(7R)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6- oxo-2-pteridinyl]amino]-3-methoxy-benzamide, to its crystallisation in the form of an hydrate with water, to a process for the manufacture thereof, and to the use thereof in a pharmaceutical composition.

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