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Trihydrochloride forms of a dihydropteridinone derivative and processes for preparation
专利权人:
Boehringer Ingelheim International GmbH
发明人:
Schmid, Rolf,Sieger, Peter,Linz, Guenter,Grauert, Matthias
申请号:
AU2007213752
公开号:
AU2007213752B2
申请日:
2007.02.07
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention relates to a specific salt of a dihydropteridione derivative, namely the trihydrochloride salt of the compound N-[trans-4-[4-(cyclopropylmethyl)-1- piperazinyl]cyclohexyl]-4-[[(7R)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6- oxo-2-pteridinyl]amino]-3-methoxy-benzamide, to its crystallisation in the form of an hydrate with water, to a process for the manufacture thereof, and to the use thereof in a pharmaceutical composition.
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