The invention is a reservoir having a piston assembly for filing and/or dispensing fluids contained in the reservoir. The refillable reservoir includes a cylinder defining a reservoir for containing a fluid a piston body axially slidable in the reservoir and a piston rod releasably fixed to the piston body for actuating the piston body. A first locking mechanism is provided between the piston body and the cylinder. A second locking mechanism is provided between the piston body and the piston rod.