James M. Apgar,Ashok Arasappan,Tesfaye Biftu,Ping Chen,Danqing Feng,Erin Guidry,Jacqueline Hicks,Ahmet Kekec,Kenneth J. Leavitt,Bing Li,Iyassu Sebhat,Xiaoxia Qian,Lan Wei,Robert R. Wilkening,Zhicai Wu
申请号:
US14420011
公开号:
US09556193B2
申请日:
2013.08.16
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The novel benzimidazole hexahydrofuro[3,2-B]furan derivatives of the present invention are activators of AMP-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention may be useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.