James M. Apgar,Tesfaye Biftu,Ping Chen,Danqing Feng,Jacqueline D. Hicks,Ahmet Kekec,Kenneth J. Leavitt,Bing Li,Iyassu Sebhat,Xiaoxia Qian,Lan Wei,Robert R. Wilkening,Zhicai Wu
申请号:
US14420024
公开号:
US20150218149A1
申请日:
2013.08.15
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Novel compounds of the structural formula (I) are activators of AMP-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention may be useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.