Compositions And Methods for Enhancing Production, Growth, Spread, or Oncolytic and Immunotherapeutic Efficacy of Interferon-Sensitive Viruses

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专利权人:

Ottawa Hospital Research Institute

发明人:

Jean-Simon Diallo,Mohammed Selman,Rozanne Arulanandam,Nicole Elise Forbes,Ramya Krishnan

申请号：

US16763013

公开号：

US20200276253A1

申请日:

2018.11.23

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Provided herein are fumaric and maleic acid-containing compounds, compositions comprising the same and methods for using such compounds to enhance production, growth, spread or titer of interferon-sensitive viruses in cells, particularly cancer and tumor cells. Also provided are methods of treating tumors or cancers in a subject by administering the compounds and compositions.

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