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The sodium salt of retinoyl-cysteic acid and retinoyl-cysteine sulfinic acid
专利权人:
发明人:
申请号:
EP09167175.0
公开号:
EP2116524B1
申请日:
2002.03.05
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
This invention relates to the synthesis of sodium salts of retinoyls derivatives, capable of potentiating the efficacy of therapeutically active compounds, for example cytotoxic compounds used in the treatment of cancer. These compounds have been shown to increase the pharmacological activity of a conventional paclitaxel formulation and to make it possible to manufacture a new formulation of paclitaxel, exhibiting improved solubility, improved storage properties, and increased therapeutic efficacy as shown in the enclosed examples.
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中国工程科技知识中心
来源网址:
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