Buschmann, Helmut Heinrich,Sola Carandell, Lluis,Benet Buchholz, Jordi,Ceron Bertran, Jordi Carles,Plata Salaman, Carlos Ramon,Tesson, Nicolas
申请号：
AU2009304235
公开号：
AU2009304235B2
申请日:
2009.10.16
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain. In a preferred embodiment, the co-crystal is a co-crystal of (-) -tramadol and (S) -naproxen (1:2)； (+) -tramadol and (R) -naproxen (1:2) or (rac) -tramadol-Hcl-celecoxib (1:1).
