A positioning device comprising a plate holder with a first fastening device for releasably fastening the plate holder to the plate, and with a second fastening device; a receptacle for an adjustment device, wherein the adjustment device includes at least one navigation device, and wherein the navigation device is designed to receive, at least in sections, an interlocking device, and/or an instrument for acting on the interlocking device and/or; wherein the receptacle comprises at least one third fastening device or is connected thereto; wherein one element from the group consisting of the second fastening device and the third fastening device is comprises a hole section with a plurality of holes, and wherein the other element of the group is designed as an insertion section, wherein the insertion section and the holes are designed for releasably connecting the second fastening device to the third fastening device.