HAUSDORFF, WILLIAM P.,SIBER, GEORGE RAINER,PARADISO, PETER R.
申请号：
CA2878579
公开号：
CA2878579C
申请日:
2006.03.31
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
An immunogenic composition having 13 distinct polysaccharide-protein conjugates and optionally, an aluminum-based adjuvant, is described. Each conjugate contains a capsular polysaccharide prepared from a different serotype of Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F) conjugated to a carrier protein. The immunogenic composition, formulated as a vaccine, increases coverage against pneumococcal disease in infants and young children globally, and provides coverage for serotypes 6A and 19A that is not dependent on the limitations of serogroup cross-protection.
