The University of Sydney;Salk Institute for Biological Studies
发明人:
Ning Ding,Michael Downes,Christopher Liddle,Ronald M. Evans
申请号：
US14921230
公开号：
US09872866B2
申请日:
2015.10.23
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present disclosure provides compositions that include a nanoparticle and a compound that increases the biological activity of the vitamin D receptor (VDR) (e.g., a VDR agonist), and methods of using such compounds to increase retention or storage of vitamin A, vitamin D, and/or lipids by a cell, such as an epithelial or stellate cell. Such methods can be used to treat or prevent fibrosis.
