To obtain a machine learning output with high accuracy and high efficiency in accordance with an imaging condition of a medical signal.SOLUTION: A medical signal processing apparatus according to an embodiment includes: a changing unit that changes a degree of activation about a unit included in a learned model in accordance with classification of an imaging condition related to a medical signal to be processed; and an application unit that applies the medical signal to the learned model after the change where the degree of activation has been changed, and generates an output signal.SELECTED DRAWING: Figure 3【課題】医用信号の撮像条件に応じて機械学習出力を高精度且つ高効率に得ること。【解決手段】実施形態に係る医用信号処理装置は、処理対象の医用信号に関する撮像条件の分類に応じて、学習済みモデルに含まれるユニットについて活性化の程度を変更する変更部と、前記活性化の程度が変更された変更後の学習済みモデルに前記医用信号を適用して出力信号を生成する適用部と、を具備する。【選択図】 図3