Hunt, Donald F.,Shabanowitz, Jeffrey,Cottine, Jennifer,English, Ann M.,Norris, Andrew,Engelhard, Victor,Cobbold, Mark,Cummings, Kara L.,Zarling, Angela,Obeng, Rebecca C.,Qian, Jie
申请号：
AU2019204422
公开号：
AU2019204422A1
申请日:
2019.06.24
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
#$%^&*AU2019204422A120190711.pdf#####ABSTRACT A set of phosphorylated peptides are presented by HLA A*0101, A*0201, A*0301, B*4402, B*2705, B*1402, and B*0702 on the surface of melanoma cells. They have the potential to (a) stimulate an immune response to the cancer, (b) to function as immunotherapeutics in adoptive T-cell therapy or as a vaccine, (c) to facilitate antibody recognition of the tumor boundaries in surgical pathology samples, and (d) act as biomarkers for early detection of the disease. Phosphorylated peptides are also presented for other cancers.
