Marquis, David Matthew,Smith, Eric Michael,Korytko, Andrew Ihor,Swanson, Barbara Anne
申请号:
AU2008229141
公开号:
AU2008229141B2
申请日:
2008.03.11
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Humanized and chimeric antibodies are provided that specifically bind humansclerostin and are characterized as having high affinity and strong neutralizingproperties. The antibodies of the invention are useful for increasing bone mass,bone mineral density and bone strength and for the treatment of various disorders,e.g., osteoporosis, in human subject.