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TNF -alpha antigen- binding proteins with increased FcRn binding
专利权人:
Glaxo Group Limited
发明人:
Ellis, Jonathan Henry,Molloy, Michael J.,Shah, Tejash,Tomlinson, Ian M.,Yasin, Ahmed
申请号:
AU2012285786
公开号:
AU2012285786B2
申请日:
2012.07.19
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The present invention provides antigen binding proteins which bind specifically to TNF-alpha. For example novel variants of anti-TNF antibodies such as adalimumab which show increased binding to the FcRn receptor or increased half life compared to adalimumab. Also provided are compositions comprising the antigen binding proteins and uses of such compositions in treatment of disorders and disease.
来源网站:
中国工程科技知识中心
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