QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY

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专利权人:

发明人:

CHANGGENG QIAN,XIONG CAI,STEPHEN GOULD,HAIXIAO ZHAI

申请号：

IN2156/DELNP/2009

公开号：

IN271928B

申请日:

2009.03.31

申请国别(地区):

IN

年份:

2016

代理人:

摘要：

The present invention relates to quinazoline containing zinc-binding moiety based derivatives that have enhanced and unexpected properties as inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK) and their use in the treatment of EGFR-TK related diseases and disorders such as cancer. The said derivatives may further act as HDAC inhibitors.

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中国工程科技知识中心

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http://www.ckcest.cn/home/